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Adolescent Girls With PCOS May Have Higher Risk Of Type 2 Diabetes.(polycystic ovarian syndrome )
2001 MAR 22 - (NewsRx.com & NewsRx.net) -- by Julie Crawshaw, staff medical writer Adolescent girls who have polycystic ovarian syndrome (PCOS) may be at higher risk for developing type 2 diabetes mellitus.
S. Arslanian and colleagues at Children's Hospital of Pittsburgh, Pennsylvania, found "serious metabolic derangements" in 12 obese adolescent girls with early syndrome PCOS. These problems included compensatory hyperinsulinemia, significant reduction in the sensitivity of peripheral tissue to insulin, and indications of hepatic insulin resistance.
The Arslanian team found fasting glucose differences between their obese subjects and the 10 obese nonhyperandrogenic girls who served as the control group for this study ("Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome," Journal of Pediatrics, 2001;138(1):38-44).
"The fasting glucose to insulin ratio was lower in the PCOS group versus the control group (1.9 ...
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