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2001 APR 4 - (NewsRx.com & NewsRx.net) --
Clinicians who care for long-term survivors of acute lymphoblastic leukemia (ALL) should test their humoral immune function to identify those at risk for severe or life threatening infections, according to a new study.
Vincent Bonagura, MD, and colleagues from Schneider Children's Hospital in New Hyde Park, New York, previously demonstrated that children who were long-term survivors of ALL have incomplete immunity from prior bacterial and viral vaccinations. Some children produced protective antibodies following vaccine challenges, however, others failed to do so.
To determine the prevalence of humoral immune defects in long-term survivors of ALL, Brodtman and colleagues tested the immune ...