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Leukemia Survivors At Risk For Life-Threatening Infections.(Brief Article)

Vaccine Weekly

| April 04, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 APR 4 - (NewsRx.com & NewsRx.net) --

Clinicians who care for long-term survivors of acute lymphoblastic leukemia (ALL) should test their humoral immune function to identify those at risk for severe or life threatening infections, according to a new study.

Vincent Bonagura, MD, and colleagues from Schneider Children's Hospital in New Hyde Park, New York, previously demonstrated that children who were long-term survivors of ALL have incomplete immunity from prior bacterial and viral vaccinations. Some children produced protective antibodies following vaccine challenges, however, others failed to do so.

To determine the prevalence of humoral immune defects in long-term survivors of ALL, Brodtman and colleagues tested the immune ...

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