AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
DTPa/Hib Single Injection Safer Than DTPw Plus Hib Given Separately.(Brief Article)
2001 APR 4 - (NewsRx.com & NewsRx.net) --
by N.R. Saltmarsh, staff medical writer - A single injection of diphtheria-tetanus-acellular pertussis (DTPa) and Haemophilus influenzae type b conjugate (Hib) vaccine causes fewer local and systemic reactions than diphtheria-tetanus-whole cell pertussis (DTPw) and Hib vaccines given separately, say researchers working in Spain.
J. Aristegui and colleagues evaluated the safety profiles of the two vaccine delivery approaches in 18-month-old children previously given three doses of DTPw and Hib vaccines.
"Children were randomized to receive DTPa/Hib (group 1; n=111) or DTPw + Hib (group 2; n=105) and were followed for up to 30 days post-vaccination," reported Aristegui et al. "All children received oral polio vaccine concomitantly. Local and general symptoms were recorded by parents on diary cards."
Parents of group 2 children reported significantly more local and systemic reactions than those in group 1. These included pain at the injection site (40% in group 1 versus 89% at the DTPw site in group 2), fever (10% for group 1 versus 56% for group 2), and fussiness (28% for group 1 and 71% for group 2).
In addition, parents reported lameness that resolved in one to five days for 21 group 2 children but only one group 1 child ("Reactogenicity and safety of DTPa vaccine and Haemophilus influenzae type b conjugate vaccine (Hib) ...
- dTpa vaccine better tolerated than DTPw vaccine in children.
- Newspaper article from: Drug Week January 30, 2004 700+ words
...antigens was similar in both groups, with 96.9% versus 92...pertactin (PRN) in the dTpa and DTPw groups, respectively. For anti...vaccine response in the dTpa group was 29.6% versus 94.4% for DTPw." "In conclusion, the dTpa...
- DPT schedule evokes Th2 tetanus and Th1 pertussis immune responses.
- Newspaper article from: Biotech Week July 28, 2004 700+ words
...and boosted with DTPa vaccine at days 21 and 28. A control group was inoculated with saline. Antibodies against B. pertussis...respectively. In contrast to previous results obtained with DTPw immunization, no IL-12 production was observed." The researchers...
- GERMANY IS FIRST WORLDWIDE LAUNCH FOR SMITHKLINE BEECHAM'S NEW ACELLULAR...
- Press release article from: PR Newswire March 21, 1995 700+ words
...pertussis) vaccines have been available since the 1940s, but the vaccine currently used is based on whole-cell pertussis (DTPw) and has been associated with a number of local and systemic side effects. "In Germany, pertussis vaccination is recommended...
- Two New Studies in the New England Journal of Medicine Show Malaria Vaccine...
- Newspaper article from: AIDS Vaccine Week December 22, 2008 700+ words
...which found a similar level of efficacy for RTS,S/AS02 when it was given in a staggered fashion with the administration of DTPw/Hib vaccine(4). "This finding has a very strong implication for protecting infants: RTS,S/AS efficacy data are very...
- GAVI and GlaxoSmithKline Deliver First Vaccines to Africa In New Vaccine...
- Press release article from: PR Newswire April 6, 2001 700+ words
The Global Alliance for Vaccines and Immunization Brings First Shipment of DTPw-HB Vaccine to Mozambique PHILADELPHIA, April 6 /PRNewswire/ -- Representatives of the Global Alliance for Vaccines and Immunizations...
- Suit against former judge asserts harassment of retarded. (William O'Donnell,...
- Press release article from: PR Newswire August 22, 1989 700+ words
...HARASSMENT OF RETARDED PHILADELPHIA, Aug. 22 /PRNewswire/ -- The Devereux Foundation, a non-profit corporation which provides group homes for retarded people, today filed a federal lawsuit against William O'Donnell, a former Chester County judge, his...
- Players.(Florida executive appointments)(Brief Article)
- Magazine article from: Florida Trend May 1, 2001 700+ words
...Yackira vice president and CFO. Yackira was most recently president of FPL Energy, a subsidiary of Juno Beach-based FPL Group, and was formerly CFO of FPL and its primary subsidiary, Florida Power & Light Co. He replaces Bob Zobel, who has...
- Counting on Growth.(Dean E. McQuiddy of Sawgrass Asset Management)(Brief...
- Magazine article from: Florida Trend Finotti, John May 1, 2001 700+ words
...focus on small caps is paying off for a group of former Barnett Bank money managers...in the consumer sector. The three main groups we have are home building, retailers and...Brinker International (NYSE-EAT), CBRL Group (Nasdaq-CBRL), Jack in the Box (NYSEJBX...
Source: HighBeam Research, DTPa/Hib Single Injection Safer Than DTPw Plus Hib Given...