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2001 MAR 15 - (NewsRx.com & NewsRx.net) -- by Maryclaire Lindgren, staff medical writer -- Salivary gland scintigraphy can be used to measure saliva gland secretions and to diagnose disease severity in Sjogren's syndrome patients.
Characterized by dryness of the mucus membranes, Sjogren's syndrome mainly affects women. W. Aung and associates at the Tokyo Medical and Dental University in Japan, sought to quantify this dryness via scintigraphy, which shows radioactive saliva secreted by the parotid and submandibular glands.
The technique enabled the researchers to determine the histopathic grade of their patients ("Study of quantitative oral radioactivity in salivary gland scintigraphy and determination of the clinical stage of Sjogren's Syndrome," Journal of Nuclear Medicine, 2001;42(1):38-43).
"New oral activity indices correlated with the stage of Sjogren's syndrome, and these quantitative oral indices together with certain glandular parameters (mainly maximum accumulation and uptake ratio of the submandibular gland) were found to be sensitive enough to distinguish the disease severity of Sjogren's syndrome," Aung et al. reported.
Salivary gland scintigraphy was performed on 70 Sjogren's syndrome patients, using lemon juice for stimulation. Aung's ...
Source: HighBeam Research, Salivary Gland Scintigraphy Aids In Diagnosing Disease...