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Maintenance Treatment Is Unnecessary After Successful HAART.(highly active antiretroviral therapy)

Vaccine Weekly

| March 14, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 MAR 14 - (NewsRx.com & NewsRx.net) --

by Michael Greer, staff medical writer -- Maintenance treatment for retinitis isn't needed after successful highly active antiretroviral therapy (HAART), according to researchers in France.

C. Katlama and colleagues at the Hopital Pitie-Salpetriere assessed the risks of discontinuing maintenance therapy for cytomegalovirus (CMV)-related retinitis in HAART patients.

After 48 weeks without any preventive treatment, they found that the patients studied had only a 2% chance of relapsing. The chances of a reccurrence of any type of CMV illness was only 4% over that time period, according to their report in the journal AIDS.

The study participants had been undergoing HAART for a median period of 18 months, Katlama et al. said, and showed at least 75x10(6) CD4 cells per liter of blood and a viral load of less than 30,000 copies per milliliter. All asymptomatic patients tested negative for CMV blood markers ("Discontinuation of maintenance therapy for cytomegalovirus retinitis in HIV-infected patients receiving highly active antiretroviral therapy," AIDS, ...

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