AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Peptide-Based Vaccine Has Potential.(cancer vaccine)
2001 MAR 7 - (NewsRx.com & NewsRx.net) --
by Michelle Marble, staff medical writer -- Peptide mapping results in discovery of potential anticancer epitopes, researchers in England say.
"The human epithelial mucin MUCI is over-expressed in more than 90% of carcinomas of the breast, ovary, and pancreas as well as in some other tumors, making it a potential target for tumor immunotherapy," wrote L.C. Heukamp and colleagues, Guy's Hospital, London, in the International Journal of Cancer.
"We have identified several MUCI-derived peptides mapping outside the variable number tandem repeat region that comply with the peptide-binding motif for HLA-A*0201 and that become processed into stable major histocompatibility complex-peptide complexes as assessed by in vitro assays."
The researchers conducted their experiments in A2/K-b transgenic mice. They found three peptides, MUC79-87 (TLAPATEPA), MUC167-175 (ALGSTAPPV), and MUC264-272 (FLSFHISNL), that elicited peptide-specific cytotoxic T lymphocyte (CTL) immunity in these mice.
This immunity protected the mice against ...
- MichBio Launches Resource Locator on Web Site; MUCI and MichBio work together...
- Press release article from: PR Newswire September 8, 2004 700+ words
...Universities Commercialization Initiative (MUCI) to provide better access to commercialized...concise list of available resources. "MUCI is very excited to be collaborating with...said Tina Bissell, business manager for MUCI. "The merging of the organizations...
- Expression of MUCI splice variants correlates with cell lines' invasive growth.
- Newspaper article from: Genomics & Genetics Weekly January 17, 2003 700+ words
...splicing the human breast cancer associated MUCI gene codes for different protein products, MUCI splice variants A and B have been shown to be...nucleotide polymorphism (SNP) in exon 2 of the MUCI gene. "We now describe two new splice variants...
- Expression of MUCI splice variants correlates with cell lines' invasive...
- Newspaper article from: Cancer Weekly January 14, 2003 700+ words
...splicing the human breast cancer associated MUCI gene codes for different protein products, MUCI splice variants A and B have been shown to be...nucleotide polymorphism (SNP) in exon 2 of the MUCI gene. "We now describe two new splice variants...
- No-fault insurer's demand for medical examination allowed by MI Court of...
- Newspaper article from: Michigan Lawyers Weekly Berg, Todd C. August 1, 2005 700+ words
...the No-Fault Act," he explained. The 11-page decision is Muci v. State Farm Mutual Automobile Ins. Co., Lawyers Weekly...Mutual Automobile Insurance Company stopped paying plaintiff Anila Muci's personal injury protection (PIP) benefits, she sued...
- Deloitte Touche incorporates Porta Cachafeiro and Romero Muci.
- News wire article from: The America's Intelligence Wire December 5, 2002 700+ words
...as subsidiary of Deloittte Touche Tohmatsu in Venezuela, has incorporated Porta Cachafeiro Laria & Asociados and Romero Muci & Asociados and will lead the business & professional consulting services market. Deloitte has been in creasing...
- Protection against MUC1-expressing mouse tumors requires T cells.
- Newspaper article from: Vaccine Weekly June 9, 2004 700+ words
...injection of full length (FL) MUCI cDNA protects against subsequent challenge...Oncology. This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
- A straight line. (hiring and suspected homosexuality)(De Jure) (Column)
- Magazine article from: Phi Delta Kappan Zirkel, Perry A. April 1, 1993 700+ words
...Wichita North's principal, Cleofas Muci, interviewed Jantz but hired another applicant...only provisional certification) and, in Muci's opinion, had done a good job of coaching. Jantz sued Muci in federal court, claiming that Muci had...
- Glycoprotein inhibition by indole-3-carbinol may hold therapeutic promise.
- Newspaper article from: Drug Week June 18, 2004 700+ words
...inhibit expression of the glycoprotein MUCI may hold preventive, as well as therapeutic...pharmaceutical researchers believe. "MUCI is a large transmembrane glycoprotein overexpressed...majority of carcinomas. High expression of MUCI is associated with aggressive tumors...
- Company gives school desks to Greensburg.
- News wire article from: Wichita Eagle (Wichita, KS) August 22, 2007 700+ words
...Aug. 22--About a month ago, Darren Muci, operations director for Wichita public...tornado ravaged the town in early May. Muci checked and found Wichita didn't have...which specializes in school furniture. Muci sits on the advisory board of U.S. Communities...
- Michigan Supreme Court finds medical exam under the No-Fault Act is...
- Newspaper article from: Michigan Lawyers Weekly Stewart, Melissa P. September 3, 2007 700+ words
...from a traffic accident in which Alina Muci allegedly suffered physical and psychiatric...State Farm opted not to pay her claim, Muci filed suit, and the insurance company...that the exam be unconditional. But, Muci refused, claiming that the statute and...
Source: HighBeam Research, Peptide-Based Vaccine Has Potential.(cancer vaccine)