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SalEst Test Not Recommended as Screening Tool for Predicting Premature Labor.

Women's Health Weekly

| February 15, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 FEB 15 -- (NewsRx.com) -- The American College of Obstetricians and Gynecologists (ACOG) is not recommending the use of a new test for screening pregnant women for preterm labor.

ACOG says it cannot recommend the Salivary Estriol (E3) test ([SalEst.sup.*]) - recently approved by the U.S. Food and Drug Administration (FDA) - because it produces a high percentage of false-positive results and could potentially add significant cost and unnecessary interventions to prenatal care.

The [SalEst.sup.*] was recently approved by the FDA to predict the risk of spontaneous premature labor leading to preterm delivery within 72 hours in women who are less than 37 weeks pregnant. The [SalEst.sup.*] tests saliva samples for an increase in levels of estriol, the estrogen hormone that plays a key role in labor leading to delivery.

Preterm labor is defined as labor occurring before ...

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