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2001 FEB 8 - (NewsRx.com) -- Women who reach a normal weight after previous obesity have different metabolic profiles than women who have never been overweight, according to a paper in the American Journal of Clinical Nutrition.
The study by Anne Raben and colleagues provides comparative information on metabolic reactions to either a high-fat, high-starch, or high-sucrose diet. The participants included 18 normal-weight women, of whom eight were post-obese (PO) and 10 were never-obese (NO). The PO women had previously been an average of 38% overweight and had been weight-stabilized for at least two months.
In a crossover design, the PO and NO subjects consumed as much as they wished of either a high-fat diet, a high-starch diet, or a high-sucrose diet for 14-day periods. On day 1 and day 15 of each dietary period, weight, body composition, and plasma levels of glucose, lactate, insulin, triacylglycerols, and other metabolic markers were measured.
Body weight decreased during the high-starch diet by an average of 0.7 kg in all participants, but did not change significantly during the other two diets. Among both groups, a steeper rise in ...