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Metabolism in Women After Weight Loss Varies from that of Never Overweight Women.

Women's Health Weekly

| February 08, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 FEB 8 - (NewsRx.com) -- Women who reach a normal weight after previous obesity have different metabolic profiles than women who have never been overweight, according to a paper in the American Journal of Clinical Nutrition.

The study by Anne Raben and colleagues provides comparative information on metabolic reactions to either a high-fat, high-starch, or high-sucrose diet. The participants included 18 normal-weight women, of whom eight were post-obese (PO) and 10 were never-obese (NO). The PO women had previously been an average of 38% overweight and had been weight-stabilized for at least two months.

In a crossover design, the PO and NO subjects consumed as much as they wished of either a high-fat diet, a high-starch diet, or a high-sucrose diet for 14-day periods. On day 1 and day 15 of each dietary period, weight, body composition, and plasma levels of glucose, lactate, insulin, triacylglycerols, and other metabolic markers were measured.

Body weight decreased during the high-starch diet by an average of 0.7 kg in all participants, but did not change significantly during the other two diets. Among both groups, a steeper rise in ...

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