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Treatment Might Include Gene Therapy and Designer Antibiotics.(Brief Article)
2001 FEB 21 - (NewsRx.com & NewsRx.net) --
Gene therapy to cure hereditary lung disorders, new treatments for asthma, and "designer" antibiotics to eradicate chronic lung infections are among the future advances that might be on the horizon in the treatment of lung disease.
Ronald G. Crystal, MD, of Weill Medical College of Cornell University, New York, New York, examined advances over the past quarter century in the treatment of lung disease, and looked ahead at research opportunities and advances in lung disease at a recent press briefing titled "Opportunities for Medical Research in the 21st Century," the briefing was a collaboration between the Albert and Mary Lasker Foundation and The Journal of the American Medical Association (JAMA, February 7, 2001;285:612-618).
"Cutting-edge research in lung disease is centered on understanding the lung as a genetically determined, complex, biological organ that mediates gas exchange and defends against a hostile environment," Crystal says.
Lung diseases include asthma, chronic obstructive pulmonary disease (COPD, including bronchitis and emphysema), pneumonia, interstitial (fibrotic) and inhalation disorders, and pulmonary embolism. According to background information cited in the article, lung disease accounted for 251,000 deaths in the United States in 1998.
Progress in the fight against lung disease has been mixed, but important achievements have been made over the past 25 years. The most recent research has focused on the lung as a biological organ, applying biochemistry, cell biology, molecular biology, and genetics to understanding lung function in health and disease. "These efforts, together with epidemiologic methods and improvements in diagnosis have led to remarkable advances in the understanding, prevention, and treatment of lung disease," Crystal notes.
Technological advances employed in the diagnosis and treatment of lung disease include fiberoptic bronchoscopy, laser methods, and computed tomography of the chest.
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Source: HighBeam Research, Treatment Might Include Gene Therapy and Designer Antibiotics.(Brief...