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Vaccination Protects Adult Community.(Brief Article)
2001 FEB 21 - (NewsRx.com & NewsRx.net) --
by Michelle Marble, staff medical writer -- Researchers in Sweden conducted a study to see if adult vaccination could be used to help stem the tide of a diphtheria epidemic in the former Soviet Union.
The researchers wanted to raise adult immunity to diphtheria in Stockholm with a vaccination campaign. "The rationale behind the campaign, conducted during 1995-1996, was the re-emergence of epidemic diphtheria in the countries of the former Soviet Union and earlier surveys of immunity to diphtheria showing low levels of protection in adults," said B. Christenson and colleagues, Karolinska Hospital.
"The impact of the vaccination campaign was measured by recording the age and sex of vaccinees, the type and number of vaccine doses given, and any side effects," the researchers said ("Impact of a vaccination campaign on adult immunity to diphtheria," Vaccine, 2000;19(9-10):1133-1140).
In 1998-1999, the researchers evaluated the effect on immunity that occurred as a result of the 1995-1996 vaccination program. They measured the neutralizing antibodies in blood samples from 1,863 inhabitants, chosen by random stratified sampling.
In the vaccination phase, those without documented previous vaccination were given three doses of diphtheria (D) or diphtheria-tetanus (DT) vaccine; those with documented previous vaccination were given a booster dose. According to the authors, the DT vaccine, with the D component purified before toxoiding, contained 15 Lf of D and 7.5 Lf of T ...
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Source: HighBeam Research, Vaccination Protects Adult Community.(Brief Article)