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Chronic Stress Modulates Adult Immune Responses.(Brief Article)
2001 FEB 21 - (NewsRx.com & NewsRx.net) --
by Michelle Marble, staff medical writer -- According to a study from the United States, adults with chronic stress do not maintain long-term immunity after vaccinations.
"Influenza and pneumonia account for significant morbidity and mortality, particularly in older individuals," stated R. Glaser and colleagues, Ohio State University. "Previous studies have shown that spousal caregivers of patients with dementia have poorer antibody and virus specific T-cell responses to an influenza virus vaccine relative to non-caregiving control subjects."
Glaser et al. published the results of their study in the journal Psychosomatic Medicine ("Chronic stress modulates the immune response to a pneumococcal pneumonia vaccine," Psychosomatic Medicine, 2000;62(6):804-807).
"This study tested the hypothesis that stress can also significantly inhibit the immunoglobulin G (IgG) antibody response to a pneumococcal bacterial vaccine," continued the researchers. "We measured antibody titers of current caregivers, former caregivers, and control subjects after vaccination with a pneumococcal bacterial vaccine."
The study showed that caregivers had deficits in antibody responses to vaccination relative to controls and former caregivers. The groups ...
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Source: HighBeam Research, Chronic Stress Modulates Adult Immune Responses.(Brief Article)