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Mutation Rate of Epstein-Barr Virus Protein Differs by Ethnicity in NPC Patients.(Brief Article)

Cancer Weekly

| February 20, 2001 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 FEB 20 - (NewsRx.com & NewsRx.net) --

A genetic twist in Epstein-Barr virus-related nasopharyngeal carcinoma has been discovered.

University of Toronto researchers found that mutations within the latent membrane protein-1 (LMP1) of the Epstein-Barr virus (EBV) occur at different rates among Chinese, Caucasian, and Inuit patients with nasopharyngeal carcinoma (NPC).

According to M. Daddario and P. Chauvin, "Many studies have characterized carboxy-terminal mutations within LMP1. Errors in this area are critical since this portion contains sequences responsible for LMP1 targeting, half-life, and association with host-cell proteins. Although data …

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Source: HighBeam Research, Mutation Rate of Epstein-Barr Virus Protein Differs by Ethnicity in...

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