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Influenza Vaccination Reduces Risk of Recurrence.(Brief Article)

Vaccine Weekly

| February 14, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 FEB 14 - (NewsRx.com & NewsRx.net) --

- by Michelle Marble, staff medical writer -- Reducing the incidence of upper respiratory infection may reduce the risk of recurrent heart attack.

"Numerous studies have suggested that microbial agents may promote atherosclerosis," wrote M. Naghavi and colleagues, University Texas. "A smaller body of research has suggested that acute respiratory infection may be a risk factor for myocardial infarction (MI). We hypothesized that influenza vaccine might reduce the risk of recurrent MI in patients with documented coronary heart disease (CHD)."

The researchers conducted a case-control study incorporating 218 CHD patients who were seen at the Memorial Hermann Hospital in Houston, Texas, during the influenza season of October 1997 through March 1998. Patients who experienced a new MI during this time period were classified as the case group. Patients who did not experience a new MI or unstable angina were assigned to the control group.

Data for the study were collected by structured reviews of patients' charts followed by a telephone survey of the same patients. Results were adjusted for patient history of influenza vaccination in previous years.

Multivariate logistic regression analysis revealed that the risk of MI was associated with current hypertension (OR 4.96, 95% CI: 2.06-11.96, P

Although univariate analysis showed a significant association of ...

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Source: HighBeam Research, Influenza Vaccination Reduces Risk of Recurrence.(Brief Article)

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