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Phase IIa Clinical Trial of Monoclonal Antibody Initiated.(Brief Article)

Vaccine Weekly

| January 17, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 JAN 17 - (NewsRx.com & NewsRx.net) -- Abgenix, Inc. (ABGX), Fremont, California, announced the start of a Phase IIa multi-center clinical trial of ABX-IL8 in patients with rheumatoid arthritis.

The company is also conducting a Phase IIa clinical trial with ABX-IL8 in patients with moderate-to-severe psoriasis, and expects to report results of this study in the first quarter of 2001.

R. Scott Greer, Abgenix, stated, "ABX-IL8 is the first fully human antibody created using our XenoMouse technology, and we hope to broaden the number of patients who could benefit from this promising new therapy."

The Phase IIa trial is a double-blind, placebo-controlled study designed to evaluate the efficacy and safety of ABX-IL8 in rheumatoid arthritis. A total of 132 patients across 20 clinical sites in the U.S. will participate in the study.

Patients will receive a total of four doses of ABX-IL8 every three weeks ...

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Source: HighBeam Research, Phase IIa Clinical Trial of Monoclonal Antibody Initiated.(Brief...

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