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Use of cDNA Suggested for Investigating Potential Flavivirus Vaccines.(Brief Article)
2001 JAN 17 - (NewsRx.com & NewsRx.net) -- Researchers at the Oswaldo Cruz Institute in Brazil think new flavivirus vaccines may result from recombinant DNA technology.
"A live attenuated virus is used as a cost-effective, safe, and efficacious vaccine against yellow fever, but no other live flavivirus vaccines have been licensed," noted M.C. Bonaldo and colleagues ("The yellow fever 17D vaccine virus as a vector for the expression of foreign proteins: Development of new live flavivirus vaccines," Mem Inst Oswaldo Cruz, 2000;95 Suppl 1:215-23).
They propose using "cDNAs encompassing the whole viral genome to generate infectious RNA after in vitro transcription." Genetic mapping of viral functions could be accomplished via this approach, they said, as well as "the design of viral mutants with ...
- Crucell and WRAIR Sign CRADA to Evaluate PER.C6 Technology for Development of...
- News wire article from: Europe Intelligence Wire December 22, 2005 700+ words
(From Hugin) Leiden, The Netherlands, December 22, 2005 - Dutch biotechnology company Crucell N.V. (Euronext, NASDAQ: CRXL) announced today that it has signed a Cooperative Research and Development Agreement (CRADA) with the Walter Reed Army Institute of Research (WRAIR) to evaluate Crucell's
- Reports from Oswaldo Cruz Foundation highlight recent research in lymphoma.
- Newspaper article from: Blood Weekly September 25, 2008 700+ words
...wrote M.A. Stimamiglio and colleagues, Oswaldo Cruz Foundation (see also Lymphoma). The researchers...Stimamiglio, Laboratory on Thymus Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Manguinhos, Rio...
- All aboard for Samba! Chaotic, noisy, sweaty fun--that's National Samba Day on...
- Magazine article from: Latin Trade Downie, Andrew March 1, 2004 700+ words
...samba trains. The trains depart for Oswaldo Cruz, the neighborhood that was home to...Day to play on the trains heading for Oswaldo Cruz, one in each car. The tradition has...Come. The train shuddered to a halt in Oswaldo Cruz just before 9 p.m. and a mass of...
- Oswaldo Cruz Foundation and Genzyme Corporation Form Collaboration To Advance...
- Press release article from: PR Newswire July 23, 2007 700+ words
...CAMBRIDGE, Mass., July 23 /PRNewswire-FirstCall/ -- The Oswaldo Cruz Foundation (Fiocruz) and Genzyme Corp. today announced...the world," said Paulo Buss, M.D., president of the Oswaldo Cruz Foundation. "In Brazil, with the support of the health...
- Researchers from Oswaldo Cruz Institute detail new studies and findings in the...
- Newspaper article from: Hepatitis Weekly March 2, 2009 700+ words
...carriers in Brazil," wrote L.M. Villar and colleagues, Oswaldo Cruz Institute. The researchers concluded: "In the present...contacting L.M. Villar, Viral Hepatitis Laboratory, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Brazil. The publisher...
- Researchers from Oswaldo Cruz Institute report details of new studies and...
- Newspaper article from: Hepatitis Weekly May 4, 2009 700+ words
...corticosteroids," wrote Almeida A.J. de and colleagues, Oswaldo Cruz Institute (see also Thrombocytopenia Therapy). The researchers...Hepatitis Laboratory, Pav Helio & Peggy Pereira, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil. The...
- New human t-lymphotropic virus study findings recently were published by...
- Newspaper article from: Blood Weekly September 25, 2008 700+ words
...and 23 at 100microM," wrote F. Grassi and colleagues, Oswaldo Cruz Foundation. The researchers concluded: "Our results indicate...Grassi, Advanced Laboratory of Public Health, CPQGM - Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil. The...
- Brazil's Oswaldo Cruz Foundation, the largest Latin American biomedical...
- Magazine article from: Chemistry and Industry September 24, 2007 700+ words
Brazil's Oswaldo Cruz Foundation, the largest Latin American biomedical research institution and US biotech firm Genzyme have formed a research collaboration...
- Emergence and control of zoonotic viral encephalitides.(Book Review)
- Magazine article from: Emerging Infectious Diseases Pappaioanou, Marguerite December 1, 2004 700+ words
...The book finishes with presentations on a novel principle of attenuation for developing new generation live flavivirus vaccines, on tick-borne encephalitis, and on a recombinant vaccine developed from a canarypox virus carrying the prM...
- OraVax Acquires Chimeric Vaccine Technology From St. Louis University Patent...
- Press release article from: PR Newswire September 16, 1997 700+ words
...in travelers to these regions. Under the terms of the agreement OraVax has licensed the rights to "Chimeric Flavivirus Vaccines" invented by Dr. Thomas Chambers, Associate Professor, Department of Microbiology and Immunology at St. Louis...
Source: HighBeam Research, Use of cDNA Suggested for Investigating Potential Flavivirus...