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2000 DEC 27 - (NewsRx.com & NewsRx.net) -- Human clinical trials are under way on an innovative peptide-based therapy developed at the University of Arizona (UA) College of Medicine that researchers hope will allow people infected with HIV to maintain good health without ever developing the symptoms associated with AIDS.
The therapy also may be useful in maintaining the health of older individuals, who often have poorly functioning immune systems, as well as for individuals with autoimmune disorders.
The Phase I human clinical trials, which will involve 18 patients, are taking place in San Francisco, California. In repeated studies, the UA-developed "T-cell receptor peptide therapy" prevented development of abnormal immune responses in mice infected with an AIDS-like retrovirus, maintaining normal immune responses seen in healthy mice.
The therapy was developed by John Marchalonis, PhD, chairman of the UA Department…
Source: HighBeam Research, Clinical Trials Under Way to Boost Immune System.