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ACCORDING TO THE NATIONAL HEADACHE Foundation in Chicago, Americans spend more than $4 billion annually on drugs to stop migraine pain. Pharmaceutical companies had largely dismissed the headache market until Imitrex was released by Glaxo Wellcome in 1997, when it generated $840 million in worldwide sales. Since that time, there have been new scientific hypotheses about migraine pain that have fueled new research for migraines. CenterWatch has identified approximately 18 drugs in clinical testing for migraines and at least eight others close to entering early phases of clinical testing. It is estimated that pharmaceutical and biotech companies will spend between $45 million to $65 million to conduct clinical trials among the more than 100 million migraine suffers in 1998.
There are no known cures for migraine but only treatments for its symptoms and these treatments are not yet wholly effective. Furthermore, scientists do not understand all the causes of migraines. Most experts believe that migraine symptoms are the result of nerve, chemical or…