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Massachusetts Biotech Firm Expects Human Trials for Anti-cancer Protein.

Knight Ridder/Tribune Business News

| September 17, 1999 | Saltus, Richard | COPYRIGHT 1999 Knight-Ridder/Tribune Business News. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Knight Ridder/Tribune Business News

Sep. 17 -- A potent new cancer-fighting protein discovered in the Boston lab of Dr. Judah Folkman can be made by slightly altering a drug that's already on the market, and therefore could enter human trials as early as next year, say officials of a Framingham biotech firm.

The new protein seems to be at least as powerful as endostatin, the widely publicized tumor-starving drug also discovered in Folkman's lab. Endostatin is about to enter its first, long-awaited human tests in Boston.

Called antiangiogenic antithrombin, or aaAT, the new protein is being described publicly for the first time today, in the current issue of the journal Science.

Genzyme Molecular Oncology in Framingham, which has licensed ...

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