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New Diabetes Treatments May Flourish at New Jersey-Based Firm's Expense.

Knight Ridder/Tribune Business News

| April 29, 1999 | Shook, David | COPYRIGHT 1999 Knight-Ridder/Tribune Business News. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Knight Ridder/Tribune Business News

Apr. 30 -- Two powerful medicines that help diabetics better use their own insulin are poised to enter the U.S. market following preliminary Food and Drug Administration approval last week.

The drugs, however, may flourish at the expense of Warner-Lambert Co.'s Rezulin, a diabetes treatment used by 1.6 million people that, in rare circumstances, has been linked to death or liver failure. Which of the drugs will emerge as the leader is unclear, analysts and doctors said Thursday.

Takeda Chemical Industries' Actos and SmithKline Beecham's Avandia represent the second generation of so-called glitazones. Rezulin was the first. This class of drugs makes muscle cells…

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