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Rescue thrombolysis for failure of primary thrombolysis cannot be justified.
EDITOR--Drenth et al suggest a policy of repeat thrombolysis if initial thrombolysis fails,[1] but their arguments are flawed.
Firstly, they state that a routine policy of rescue angioplasty cannot be justified from a review of the literature, although they fail to mention that the trial by Ellis et al showed a significant reduction in the incidence of death or severe heart failure in the rescue angioplasty group compared with the conservative group.[2]
Secondly, there are far fewer published data from randomised trials comparing the use of rescue thrombolysis with conservative treatment, yet the authors claim that these data support their current practice. …
