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Hormone therapy (HT) may not provide a protective effect against emerging depression in older postmenopausal women, according to results of a large-scale study conducted in France. The three-city study investigated whether HT is associated with current depressive symptoms in 4,069 community-dwelling postmenopausal women (mean age, 74 years) without dementia who were randomly recruited from Bordeaux, Dijon, and Montpellier between 1999 and 2001. After controlling for sociodemographic variables and physical health, investigators found no significant association between baseline HT use and incident depressive symptoms. However, there was a significantly greater risk of new-onset depressive …