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On 7 Sep 2010, SymBio Pharmaceuticals Ltd and Eisai Co Ltd announced that Eisai's Singapore subsidiary Eisai (Singapore) Pte Ltd launched bendamustine hydrochloride ("bendamustine") in Singapore under the brand name Symbenda as a treatment for low-grade non-Hodgkin's lymphoma and chronic lymphatic leukemia. Bendamustine is the subject of a license agreement concluded between the two companies in May 2009, in which SymBio granted Eisai the exclusive rights to develop and market the agent in Singapore and South Korea. A regulatory application seeking approval of bendamustine was submitted to the Singapore health authorities (Health Sciences Authority: HSA) by SymBio on 24 Dec 2008 and was …