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Systemic and antigen-specific immune responses in patients treated with cancer vaccine BPX-101 correlate with clinical response.

Chemical Business Newsbase

Bellicum Pharmaceuticals Inc announced the presentation of interim Phase I/II efficacy data for BPX-101, a novel dendritic cell vaccine for metastatic castrate resistant prostate cancer (mCRPC), in a Late Breaking poster at the American Association for Cancer Research (AACR) 101st Annual Meeting 2010 held in Washington DC. Guru Sonpavde, MD, Principal Investigator at The University of Texas Health Science Center-Houston, presented interim Phase I/II data that suggest a correlation between dose-related variations in levels of inflammatory serum markers and measurable clinical response in patients treated with BPX-101. Correlative PSA declines, suppression of serum IL-6, and …

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