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Medical University of South Carolina publishes research in neurodegenerative disease.
According to recent research from the United States, "Down syndrome (DS) individuals develop several neuropathological hallmarks seen in Alzheimer's disease, including cognitive decline and the early loss of cholinergic markers in the basal forebrain. These deficits are replicated in the Ts65Dn mouse, which contains a partial trisomy of murine chromosome 16, the orthologous genetic segment to human chromosome 21."
"Oxidative stress levels are elevated early in DS, and may contribute to the neurodegeneration seen in these individuals. We evaluated oxidative stress in Ts65Dn mice, and assessed the efficacy of long-term antioxidant supplementation on memory and basal forebrain pathology. We report that oxidative stress was elevated in the adult Ts65Dn brain, and that supplementation with the antioxidant vitamin E effectively reduced these markers. Also, Ts65Dn mice receiving vitamin E exhibited improved performance on a spatial working memory task and showed an attenuation of cholinergic neuron pathology in the basal forebrain," wrote J. Lockrow and colleagues, Medical University of South Carolina (see also Neurodegenerative Disease).
The researchers concluded: "This study provides evidence that ...
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...United States. The Medical University of South Carolina was chartered in...Library of the Medical University of South Carolina, specifically...archives of the Medical University of South Carolina from 1824 to 1860...
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...across the entire continuum of care, Medical University of South Carolina (MUSC) has launched a $19.7...range of healthcare needs." About Medical University of South Carolina Medical University of South Carolina has served the...
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...collection of work by South Carolina artists," said Mark...in Charleston, the Medical University of South Carolina is the one of the oldest...Kathleen Ellis of Medical University of South Carolina, +1-843-792...
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...Columbia/HCA and the Medical University of South Carolina announced a mutual...President of the Medical University of South Carolina, reevaluated the...separately." The Medical University of South Carolina and Columbia...
- LanVision Systems, Inc. Wins Contract Through the State of South Carolina With...
- Press release article from: PR Newswire August 18, 1998 700+ words
...Correspondence(TM) and OmniVision viewing module, which will be implemented at the Medical University of South Carolina. The Medical University of South Carolina ("MUSC"), located in Charleston, is a state university comprised of six colleges...
Source: HighBeam Research, Medical University of South Carolina publishes research in...