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Findings in hormones reported from University of Lund.

Women's Health Weekly

| June 04, 2009 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

According to a study from Lund, Sweden, "The hormonal system for induction of term and preterm labour is not fully understood. Therefore, we investigated myometrial gene expressions for neurohypophyseal hormones and their receptors, prostaglandin F2 and ovarian steroid receptors in women delivered by Caesarean section."

"Myometrial tissue for real time PCR was collected from 39 women delivered at term before and after the onset of labour and preterm. Women delivered electively at term had significantly higher oxytocin receptor mRNA expressions (2.520.37 oxytocin receptor/actin; medianSEM) than those delivered with ongoing labour at term (1.010.34; p=0.015) and those at preterm (1.080.25; p=0.004). Sub-analyses revealed that the difference at term pregnancies solely was related to patients receiving oxytocin during labour (p=0.007). These patients had higher oxytocin peptide mRNA levels than those without labour at term (p=0.009). PGF2 receptor mRNA concentrations were 27.803.55, 11.462.87 and 19.545.52 PGF receptor/actin, respectively, for the groups. Women without labour at term had higher concentration than those with labour (p=0.005)," wrote R. Liedman and colleagues, ...

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Source: HighBeam Research, Findings in hormones reported from University of Lund.

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