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Research in the area of adverse drug reactions reported from University of Maryland.

Women's Health Weekly

| June 04, 2009 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

"We determined the clinicodemographic factors associated with complications of continence procedures, the impact of concomitant surgery on the complication rate and the relationship between the incidence of cystitis and the method of postoperative bladder drainage. We reviewed serious adverse events and adverse events in the Stress Incontinence Surgical Efficacy Trial, a randomized trial comparing Burch colposuspension to the autologous rectus fascial sling," scientists in the United States report (see also Adverse Drug Reactions).

"Clinicodemographic variables were analyzed to determine those associated with adverse events using logistic regression analysis. Complications were stratified based on the presence or absence of concomitant surgery. Differences in complication rates (controlling for concomitant surgery) and cystitis rates (controlling for the bladder emptying method) were compared using Fisher's exact test. Blood loss (p = 0.0002) and operative time (p

The researchers concluded: "Complications were associated with surgical factors and not with patient related factors."

Chai and colleagues published their study in the Journal of Urology (Complications in Women Undergoing Burch Colposuspension Versus Autologous Rectus Fascial Sling for Stress Urinary Incontinence. Journal of Urology, 2009;181(5):2192-2197).

For more information, contact T.C. Chai, University of Maryland Baltimore, Division Urology, 22 S Greene St., S8D18, Baltimore, MD 21201, USA.

Publisher contact information for the Journal of Urology is: Elsevier Science Inc., 360 ...

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