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Atomoxetine: serious liver injury.(Safety and Efficacy Issues)

WHO Drug Information

| January 01, 2009 | COPYRIGHT 1999 World Health Organization. (Hide copyright information)Copyright

United States of America -- The Food and Drug Administration (FDA) continues to receive reports of serious liver injury in patients given atomoxetine. Atomoxetine received FDA approval on 26 November 2002 as the first non-stimulant medication used for the treatment of attention deficit hyperactivity disorder (ADHD) in children (aged 6 years and above) and adults (1).

Atomoxetine's therapeutic action is believed to be due to its selective inhibition of norepinephrine reuptake. From the year 2002 to 2007, approximately 3.3 million patients received a prescription for atomoxetine in the United States. Of those, approximately 2.1 million patients (64%) were children aged 17 years …

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