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The claim. Makers of various items sold over the counter and online claim their products "cleanse" the large intestine, or colon. Proponents say that "detoxifying" with those products prevents waste from building up and toxic substances and parasites from being absorbed into the bloodstream.
The check. Our reporters searched for published scientific research, reviewed the data at the Natural Medicines Comprehensive Database, an independent, evidence-based compendium that evaluates natural products for ConsumerReportsHealth.org, and interviewed medical experts.
Bottom line. We found insufficient reliable evidence that colon-cleansing products are safe or effective for improving general health. But we did find some cause for concern. When they are administered too often, laxatives and enemas might prevent normal bowel movements or lead to a potentially deadly depletion of vital electrolytes.