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Research from National Taiwan University in lupus provides new insights.(Report)
According to recent research published in the journal Lupus, "Previous study showed that soy isoflavone supplement alleviates disease severity in autoimmune-prone mice. As the ethyl acetate extract of alfalfa sprout (AS) has selective oestrogenic and anti-inflammatory activity, this study evaluated the effects of alfalfa sprout ethyl acetate extract (ASEA) on disease severity of systemic lupus erythematosus, using autoimmune-prone female MRL-lpr/lpr mice."
"In Experiment 1, five groups of 12-week-old female mice were per oral treated with vehicle (control), lyophilized AS (550 mg wt/kg BW), ASEA (ASEA, 25 mg/kg BW), coumestrol (CUM, 0.075 mg/kg BW) and tamoxifen (TAM, 0.375 mg/kg BW) as the positive control. The onset of proteinuria was delayed, and the life span was significantly longer in the ASEA and TAM groups but neither in the AS nor in the CUM groups, compared to the control. To examine the changes in the immunological parameters related to disease process, three more groups of MRL-lpr/lpr female mice (control, ASEA and TAM) were fed in a similar manner for 6 weeks in the Experiment 2. Flow cytometric analysis of splenocytes showed a significantly lower percentage of activated T cells in the ASEA and TAM groups. The ex-vivo interferon-gamma and interleukin (IL)-4 production from splenocytes and tumour necrosis factor-alpha and IL-1 beta production from peritoneal exudate cells were also significantly lower in the ASEA group compared with the ...
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- Press release article from: Business Wire January 26, 2009 700+ words
...to 1,000 Students at National Taiwan University TAIPEI CITY, Taiwan...of US$75 million to National Taiwan University (NTU) in Taipei City...Applied Mechanics of National Taiwan University. "From an academic...
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...wrote M.L. Lee and colleagues, National Taiwan University (see also Ventricular Septal Defects...information, contact C.I. Chang, National Taiwan University, National Taiwan University, Division Cardiovascular Surgery...
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...wrote E.Y.C. Hwang and colleagues, National Taiwan University, Medical Department. The researchers...obtained by contacting C.P. Chiang, National Taiwan University, National Taiwan University, College Medical, Dept. of Dental...
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...wrote H.Y. Chen and colleagues, National Taiwan University. The researchers concluded: "CBT...information, contact T.J. Tsai, National Taiwan University, National Taiwan University, College Medical, Division Nephrology...
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...wrote J.J. You and colleagues, National Taiwan University (see also Diabetic Retinopathy...information, contact C.M. Yang, National Taiwan University, National Taiwan University, Dept. of Ophthalmology, College...
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...wrote L.C. Ho and colleagues, National Taiwan University, Medical Department (see also Dialysis...information, contact C.K. Chiang, National Taiwan University, National Taiwan University, School Medical, Dept. of Internal...
- Researchers from National Taiwan University, Medical Department report details...
- Newspaper article from: Biotech Week September 17, 2008 700+ words
...wrote O.A. Ross and colleagues, National Taiwan University, Medical Department (see also Parkinson...more information, contact Y.R. Wu, National Taiwan University, National Taiwan University, College Medical, Dept. of Neurology...
- Reports from National Taiwan University advance knowledge in diabetes.
- Newspaper article from: Diabetes Week February 2, 2009 700+ words
...wrote W.C. Lee and colleagues, National Taiwan University. The researchers concluded: "Diabetes...additional information, contact H.J. Yu, National Taiwan University, National Taiwan University, Dept. of Urology, 7 Chungshan S...
