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New hydatidiform mole research reported from E. Garavaglia and co-authors.(Report)
According to recent research from Milan, Italy, "The purpose of this study was to identify prognostic factors associated with development of gestational trophoblastic neoplasia (GTN) after hydatidiform mole (HM). A retrospective analysis of 189 patients with HM was performed."
"We recorded features such as maternal age, HM history, blood group, gestational age, uterine volume at evacuation, presence of theca lutein cysts, vaginal bleeding, and transvaginal ultrasonography with color Doppler imaging. We considered risk predictors to be the presence of nodules and hypervascularization within the myometrium or endometrium (positive ultrasound imaging). An univariate and multivariate analysis, with the COX nominal logistic model, was performed. Fourteen patients experienced GTN (7.4%). After univariate analysis, uterine size (P = .0139) and positive ultrasound results (P
The researchers concluded: "None of the other prognostic factors that were evaluated was predictive of GTN development."
Garavaglia and colleagues published their study in American Journal of Obstetrics and Gynecology (Ultrasound ...
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...outcome of two cases of complete hydatidiform mole with a coexisting viable fetus and...of twin pregnancies with complete hydatidiform mole and a normal fetus." "Genetic...Dolapcioglu and colleagues (see also Hydatidiform Mole). The researchers concluded...
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...causative gene for familial recurrent hydatidiform mole (FRHM), a rare autosomal recessive...London, Imperial College (see also Hydatidiform Mole). The researchers concluded...mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the...
Source: HighBeam Research, New hydatidiform mole research reported from E. Garavaglia and...