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Scientists at National Autonomous University, Medical Department target hormones.
According to a study from Mexico, "17 beta-aminoestrogens (AEs) produce anticoagulant effects in rats contrasting with 17 beta-estradiol (EA procoagulant effects, their estrogenic effects are similar to E-2, decreasing serum luteinizing hormone (LH), increasing uterine weight (Uw), activate transcription through the ER alpha and ER beta receptors and pentolame induces progesterone (P) receptors in the anterior pituitary of ovariectomized (Ovx) rats similarly to E-2, suggesting possible effects on female rats' sexual behavior. This work evaluated the AEs prolame, butolame, pentolame compared to E-2 and estradiol benzoate (EB) as facilitators on the rat lordotic behavior."
"Dose-response curves were performed in rats by single subcutaneous (s.c.) injection (time zero)of. E-2 (approximate to 0.3, 3, 30, 60, 300 mu g/kg): EB (approximate to 0.4, 4, 40, 80, 400 mu g/kg); prolame, butolame, pentolame (approximate to 40, 400. 2000 or 4000 mg/kg), vehicle (corn oil; 300 mu L/day; = 1.2 mL/kg) as control; 24 h after, P (1 mg/rat in 100 mu L of corn oil: approximate to 4 to 5 mg/kg) was administered, and 5 to 7 h later LQ was evaluated (number of lordosis displays / number of mounts x 100). E-2. EB and AEs followed by P administration, induced lordosis in a dose-dependent manner. Prolame induced an LQEmax of 92, butolame 85. EB 81, pentolame 44 and E-2 43. The most potent was EB (LQED50 of 41 +/- 05 mu g/kg); then E-2 10 +/- mu g 2.2/kg; prolame 268 +/- 19 mu g/kg: butolame 402 +/- 21 mu g/kg, and pentolame 1037 +/- 28 mu g/kg. The AEs LQ potency decreases as length ...
- National Autonomous University publishes research in life sciences.
- Newspaper article from: Science Letter May 12, 2009 700+ words
...Blanchon and colleagues, National Autonomous University (see also Life Sciences...contact P. Blanchon, National Autonomous University of Mexico, Institute...Cancun, Life Sciences, National Autonomous University. This article was...
- National Autonomous University publishes research in physical chemistry.
- Newspaper article from: Chemicals & Chemistry July 10, 2009 700+ words
...Valencia and colleagues, National Autonomous University. The researchers concluded...contact M. Castro, National Autonomous University of Mexico, Faculty...Moment, Physics, National Autonomous University. This article was...
- National Autonomous University details research in materials science.
- Newspaper article from: Nanotechnology Weekly July 13, 2009 700+ words
...Lopezayala and colleagues, National Autonomous University. The researchers concluded...contact M.E. Rincon, National Autonomous University of Mexico, Center...Materials Science, National Autonomous University. This article was...
- National Autonomous University publishes research in conservation biology.
- Newspaper article from: Ecology, Environment & Conservation August 21, 2009 700+ words
...Ceballos and colleagues, National Autonomous University. The researchers concluded...contact G. Ceballos, National Autonomous University of Mexico, Institute...Global Warming, National Autonomous University. This article was...
- National Autonomous University details research in enzyme research.
- Newspaper article from: Proteomics Weekly August 4, 2008 700+ words
...Garcia and colleagues, National Autonomous University. The researchers concluded...J.E. Escamilla, National Autonomous University of Mexico, Institute...Research, Reductase, National Autonomous University. This article was...
- National Autonomous University reports research in materials engineering.
- Newspaper article from: Journal of Engineering June 17, 2009 700+ words
...Cruz and colleagues, National Autonomous University. The researchers concluded...contact H. Cruz, National Autonomous University of Mexico, Dept...Materials Engineering, National Autonomous University. This article was...
- Scientists at National Autonomous University publish research in peptide...
- Newspaper article from: Science Letter June 9, 2009 700+ words
...Pacheco and colleagues, National Autonomous University (see also Peptide...contact M. Soberon, National Autonomous University of Mexico, Institute...Sciences, Peptides, National Autonomous University. This article was...
- Reports from National Autonomous University advance knowledge in genetics.
- Newspaper article from: Biotech Week April 29, 2009 700+ words
...Martinezsalazar and colleagues, National Autonomous University (see also Genetics...contact D. Romero, National Autonomous University of Mexico, Center...Therapy, Treatment, National Autonomous University. This article was...
