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Colorectal cancer risks quantified.(Report)
Although the presenting features of colorectal cancer are well known, the risks they confer are less well defined. New research published in the open access journal BMC Medicine describes the exact risks posed by eight clinical features for the development of colorectal cancer in a large group of patients (see also BioMed Central).
William Hamilton led a team of researchers from the Universities of Bristol and Birmingham who studied the primary care records of 5,477 colorectal cancer patients and 38,314 controls. He said, "General practitioners (GPs) gain relatively little experience in the diagnosis of colorectal cancer because the incidence is about one per GP per year, and only a proportion of these are diagnosed in primary care. Our findings strengthen the view that rectal bleeding carries a high enough risk to warrant investigation irrespective of other symptoms. Current guidance requires persistence of bleeding for 6 weeks, or accompanying diarrhoea. In our opinion, these additional requirements are unnecessary."
The authors found that the highest risks were conferred by rectal bleeding and change in bowel habit. For men over 60 years, rectal bleeding positive predictive values (PPVs) ranged from 2.4-4.5%. For women, the figures were lower, but still in the 2-3% range. Dr Hamilton added, "Change in bowel habit is less simple: GPs contributing to the database must have been using this term very differently from the separate terms of constipation and diarrhoea, in that the PPVs for change in bowel habit were ...
- Rectal bleeding and colorectal cancer.(Letter to the Editor)
- Magazine article from: British Medical Journal Fahey, Tom Montgomery, Alan Schroeder, Knut Leung, Wai-Ching Wauters, Hans Casteren, Viviane Van March 10, 2001 700+ words
...patients with rectal bleeding subsequently developed colorectal cancer, and even...Buntinx F. Rectal bleeding and colorectal cancer in general...Does isolated rectal bleeding suggest colorectal cancer? Lancet 1993...
- Rectal bleeding and colorectal cancer in general practice: diagnostic study.
- Magazine article from: British Medical Journal Wauters, Hans Van Casteren, Viviane Buntinx, Frank October 21, 2000 700+ words
...Positive predictive values of rectal bleeding for diagnosis of colorectal cancer, stratified for age Rectal bleeding With Positive colorectal...0) Of 386 patients with rectal bleeding, 27 had colorectal cancer, giving a positive predictive...
- Rectal bleeding is associated with increased risk of distal colon cancer.
- Newspaper article from: Cancer Weekly March 23, 2004 700+ words
...Screening remains the best way to find colorectal cancer, even though rectal bleeding is associated with an increased risk of having...diagnostic value of rectal bleeding for distal colorectal cancer (CRC), or large (greater than or equal...
- GP CLINICAL: Clinical Review - Rectal bleeding.
- Magazine article from: GP January 7, 2002 700+ words
...distinguishing factors Rectal bleeding can indicate...pathology, from colorectal cancer to simple...diagnosis of colorectal cancer. Less than...advice about rectal bleeding are concerned...symptom scores. COLORECTAL CANCER RISK - General...
- New aid to identify rectal bleeding risks.(Brief Article)
- Newspaper article from: Pulse December 3, 2005 700+ words
...which patients with rectal bleeding have high risk of cancer...in primary care with rectal bleeding found only 3.4 per cent had colorectal cancer. But the prevalence...present to their GPs with rectal bleeding do not have cancer...
- Clinical: Red flag symptoms - Rectal bleeding.
- Magazine article from: GP March 20, 2009 700+ words
...presenting with rectal bleeding, only 3...diagnosed with colorectal cancer.1 The majority...excluding colorectal cancer, the following...patients with rectal bleeding. If blood...Predicting colorectal cancer risk in patients with rectal ...
- Health: Rectal bleeding termed non-malignant in 90pc cases.
- News wire article from: PPI - Pakistan Press International August 5, 2006 700+ words
...for almost 90 per cent of all rectal bleeding in women; in the other 10...She further informed that rectal bleeding is often caused by haemorrhoid...rectal ulcers, polyps and colorectal cancer. Any new onset of bleeding...
- Health: 90 per cent of rectal bleeding problems are benign.
- News wire article from: PPI - Pakistan Press International January 19, 2007 700+ words
...per cent of all episodes of rectal bleeding, and only in the remaining...people. Dr Sadaf informed that rectal bleeding is often caused by haemorrhoid...rectal ulcers, polyps and colorectal cancer. Any new onset of bleeding...
- IMPACT OF THE NURSE LED RECTAL BLEEDING CLINIC.(Abstract)
- Magazine article from: Gut Vance, M.E. Shah, S.G. Windsor, A.C. Saunders, B.P. March 1, 2001 700+ words
...Background/Aims: Rectal bleeding is a common symptom...heightened awareness of colorectal cancer leading to an increased...led open access rectal bleeding clinic was set up...session. Methods: A rectal bleeding clinic was established...
- Rectal bleeding: prevalence and consultation behaviour.
- Magazine article from: British Medical Journal Crosland, Ann Jones, Roger August 19, 1995 700+ words
...Although most cases of rectal bleeding are due to self limiting...individuals with rectal bleeding consult a general...they had experienced rectal bleeding in the past year...under half.[2] If colorectal cancer is to be detected...
Source: HighBeam Research, Colorectal cancer risks quantified.(Report)