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Tolarex, a Hadasit Bio Holdings Ltd (HBL) portfolio company, announced that it has received approval by the Ministry of Health of Israel to begin a phase I/IIa clinical trial of its treatment for graft-versus-host disease (GVHD) (see also Hadasit Bio Holdings).
The first in man trial, anticipated to begin shortly, will evaluate the safety and preliminary possible efficacy of Tolarex's therapy. Twelve patients will be enrolled at two medical centers in Israel, Hadassah University Hospital in Ein Kerem included.
The therapies that exist today to treat GVHD are based on immunological suppression or the weakening of a patient's immune system, have low efficiency, can cause severe side effects and expose the…
Source: HighBeam Research, HBL Portfolio Company Tolarex to Commence Phase I/IIa Trial of a...