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The use of multivitamins does not alter risk for several common cancers, cardiovascular disease, or death in post-menopausal women, according to a report in the Archives of Internal Medicine.
Data on 161, 808 women participating in the Women's Health Initiative "provide convincing evidence that multivitamin use has little or no influence on the risk of cancer or CVD" in this patient population, said Marian L. Neuhouser, Ph.D., of Fred Hutchinson Cancer Research Center, Seattle, and her associates.
Historically, there had been no convincing scientific data to support the use of multivitamins in healthy people, "despite the widespread use of supplements and the strong consumer beliefs about benefits," the researchers noted.
They assessed the associations between multivitamin use and several health outcomes by using data from the Women's Health Initiative (WHI) clinical trial and observational study cohorts. Both cohorts involved postmenopausal women aged 50-79 years at enrollment. The subjects were followed for a median of approximately 8 years.
The WHI "captured detailed data on dose, frequency, and duration of supplement [use]" by means of a four-page questionnaire on multivitamins, as well as direct transcription from the labels of subjects' bottles of supplements. A total of 41% of the study subjects used multivitamins.
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Source: HighBeam Research, Cancer, CVD risk not reduced by multivitamins.(CLINICAL ROUNDS)