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According to recent research from the United States, "Cumulative data on the effects of estrogen therapy (ET) on brain function in postmenopausal women suggests that ET influences cerebral metabolism and may protect against age-related declines in various domains of cognitive function. The beneficial cognitive effects of ET may relate to its modulation of the thalamic-striatum cholinergic and dopaminergic systems, as the activity of both neurotransmitter systems in the thalamus appears to be positively influenced by estrogen."
"In the current study, we attempted to evaluated regional cerebral brain metabolism utilizing [18F]-fluorodeoxyglucose positron emission tomography in 11 healthy recently-postmenopausal women on ET (ET+) in comparison to 11 recently-postmenopausal and ET-na
The researchers concluded: "The results also suggest that ET initiated at or near the menopausal transition may modulate brain aging by mediating complex sensory-motor functions."
Kenna and colleagues published their study in Neurochemical Research (Thalamo-Basal Ganglia Connectivity in Postmenopausal Women Receiving Estrogen Therapy. Neurochemical Research, 2009;34(2):234-237).
For additional information, contact N.L. Rasgon, Stanford University, ...