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Leuven University reports research in endometriosis.
"Endometriosis, defined as the ectopic presence of endometrial-like cells, is associated with infertility and pelvic pain in women. Whereas pathogenesis and spontaneous evolution of endometriosis arc still poorly understood, recurrences after surgical therapy or after medical treatment are common," scientists writing in the journal Reproductive Sciences report (see also Endometriosis).
"Spontaneous endometriosis occurs only in women and in nonhuman primates (NHPs). Inbred rhesus monkeys kept in colonies offer an attractive preclinical model to study the inheritance of spontaneous endometriosis. Baboons with spontaneous or induced endometriosis appear to be the best NHP model to study pathogenesis, pathophysiology, spontaneous evolution and new medical treatment options. In baboons, induction of endometriosis after intrapelvic injection of menstrual endometrium leads to biological changes in peritoneal cavity and in endometrium," wrote T.M. Dhooghe and colleagues, Leuven University.
The researchers concluded: "This induction process may allows the study of cause-effect ...
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Source: HighBeam Research, Leuven University reports research in endometriosis.