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Researchers' work from National University focuses on DNA research.(Report)
According to recent research published in the Journal of the American Society of Nephrology, "Leukocyte 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a surrogate marker of oxidant-induced DNA damage in patients undergoing maintenance hemodialysis (MHD). Glutathione S-transferase M1 (GST M1) is a member of the GST family of proteins, which protect cellular DNA against oxidative damage."
"This study tested the association of a common GST M1 gene polymorphism [GST M1(-)], known to produce a dysfunctional enzyme, with levels of 8-OHdG in peripheral blood leukocytes and all-cause mortality among MHD patients. Among 488 MHD patients and 372 gender-matched healthy subjects, the frequency of the GST M1(-) genotype was 63.1 and 60.2%, respectively. The GST M1(-) genotype was associated with significantly higher levels of leukocyte 8-OHdG compared with the GST M1(+) genotype, even after adjustment for potential confounders (P
The researchers concluded: "Patients without GST M1 activity are more vulnerable to oxidative stress and are at greater risk for death compared with those who possess GST M1 activity."
Lin and colleagues published their study in the Journal of the American Society of Nephrology (GST M1 Polymorphism Associates with DNA Oxidative Damage and Mortality among Hemodialysis Patients. Journal of the American Society of Nephrology, ...
- Studies from National University in the area of soil science described.
- Newspaper article from: Agriculture Week July 2, 2009 700+ words
...and colleagues, National University. The researchers...Lodeiro, La Plata National University, IBBM, Dep Ciencias...Agronomy Journal is: American Society Agronomy, 677...Soil Science, National University. This article...
- New data from National University illuminate research in construction.
- Newspaper article from: Journal of Technology October 20, 2009 700+ words
...and colleagues, National University. The researchers...Tan, Singapore National University, Dept. of Civil...Construction is: Asce-American Society Civil Engineers...Construction, National University. This article...
- Studies conducted at National University on manufacturing engineering recently...
- Newspaper article from: Journal of Engineering August 19, 2009 700+ words
...and colleagues, National University. The researchers...Zheng, Singapore National University, Control &...ASME is: ASME-American Society Mechanical Eng...Manufacturing, National University. This article...
- Reports outline environmental engineering study findings from National...
- Newspaper article from: Ecology, Environment & Conservation September 18, 2009 700+ words
...and colleagues, National University. The researchers...Chen, Singapore National University, Division Environmental...contacted at: Asce-American Society Civil Engineers...Environment, National University. This article...
- Researchers from National University report recent findings in kidney disease.
- Newspaper article from: Blood Weekly January 1, 2009 700+ words
...Journal of the American Society of Nephrology...Singapore National University Hospital...Journal of the American Society of Nephrology is: American Society Nephrology...Disease, National University. This article...
- Reports summarize heart attack research from Chungnam National University.
- Newspaper article from: Heart Disease Weekly October 25, 2009 700+ words
...Left Atrium. Journal of the American Society of Echocardiography, 2009...contact J.H. Park, Chungnam National University, School Medical, Chungnam...information for the Journal of the American Society of Echocardiography is: Mosby...
- Seoul National University reports research in fluids engineering.(Report)
- Newspaper article from: Journal of Engineering August 5, 2009 700+ words
...colleagues, Seoul National University. The researchers...Kang, Seoul National University, 599 Gwanak Ro...contacted at: ASME-American Society Mechanical Eng...Fluids, Seoul National University. This article...
- Research from National University yields new findings on parasitology.
- Newspaper article from: Science Letter April 7, 2009 700+ words
...and colleagues, National University (see also Parasitology...Viozzi, Comahue National University, Parasitology...Parasitology is: American Society Parasitologists...Parasitology, National University. This article...
