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"A prospective randomized controlled clinical study. To investigate the feasibility of a calcium phosphate cement (CaP) in balloon kyphoplasty if compared to polymethylmethacrylate (PMMA)," scientists writing in the journal Spine report (see also Calcium Phosphate Cement).
"In kyphoplasty and vertebroplasty, PMMA currently represents the standard in augmentation materials. It is characterized, however, by a lack of osseointegration and limited biocompatibility. Consequently, CaP is currently being investigated as an alternative material for vertebral augmentation. Inclusion criteria were 1 or 2 adjacent osteoporotic fractures of vertebral bodies in the thoracolumbar spine, patient age >= 65 years, and fracture age
The researchers concluded: "Because of its low resistance against flexural, tractive, and shear forces compared to PMMA, in certain constellations (burst fractures), there is a higher risk of cement failure and subsequent loss of correction."
Blattert and colleagues published their study in Spine (Suitability of a Calcium Phosphate Cement in Osteoporotic Vertebral Body Fracture Augmentation A Controlled, Randomized, Clinical Trial of Balloon Kyphoplasty Comparing Calcium Phosphate Versus Polymethylmethacrylate. Spine, 2009;34(2):108-114).
Additional information can be obtained by contacting T.R. Blattert, University Hospital, Clinic Trauma Reconstruct & Plast Surgery, University of Klinikum Leipzig AoR, Klin Unfall Wiederherstellungs & Plast Chirurg, Liebigstr 20, D-04103 Leipzig, Germany.
The publisher of the journal Spine can be contacted at: Lippincott ...
Source: HighBeam Research, Studies conducted at University Hospital on calcium phosphate cement...