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Research from Central South University has provided new data on bone research.
"Little research exists on the dynamic effects of glucocorticoids on bone mineral density (BMD) and microarchitecture of trabecular bones of rats assessed by micro-computed tomography (micro-CT). To investigate time-related changes in the BMD and microarchitecture of trabeculae in rats exposed to glucocorticoid," researchers in Changsha, People's Republic of China report (see also Bone Research).
"Female Sprague-Dawley rats were recruited into a baseline group, glucocorticoid-treated groups, or control groups. Glucocorticoid-treated rats were given daily subcutaneous injections of methylprednisolone at a dosage of 3.5 mg/kg for 1 or 9 weeks. A high-resolution micro-CT was used to identify the densitometric and microarchitectural properties of trabeculae in both the proximal metaphysis of tibiae and the sixth lumbar vertebrae (L6). Compared with baseline rats, volumetric BMD, tissue BMD, bone volume fraction, trabecular number, and degree of anisotropy of trabeculae from tibiae or L6 increased in control rats and glucocorticoid-treated rats with time; however, changes in the latter group were smaller. Compared with control rats at each time point, a decrease occurred in volumetric BMD, tissue BMD, bone volume fraction, trabecular number, degree of anisotropy, and trabecular connectivity density in trabecular bones from tibiae or L6 in glucocorticoid-treated rats. The decrease was greater in week 9 compared to week 1. Contrarily, an increase was noted in trabecular thickness, trabecular separation, and structure model index in glucocorticoid-treated rats. A time-related analysis within ...
- Central South University details research in DNA research.
- Newspaper article from: Proteomics Weekly May 11, 2009 700+ words
...Long and colleagues, Central South University. The researchers concluded...contact J.X. Wang, Central South University, College Chemical &...Analytical Chemistry, DNA, Central South University. This article was prepared...
- Central South University publishes research in pharmacokinetics.
- Newspaper article from: Biotech Week August 27, 2008 700+ words
...Xu and colleagues, Central South University (see also Pharmacokinetics...contact Y.G. Zhu, Central South University, Xiangya Hospital 2...Therapy, Treatment, Central South University. This article was prepared...
- Research from Central South University has provided new information about...
- Newspaper article from: Cancer Gene Therapy Week June 1, 2009 700+ words
...Li and colleagues, Central South University. The researchers concluded...by contacting G. Li, Central South University, Cancer Research Institute...Pulmonology, Treatment, Central South University. This article was prepared...
- Researchers from Central South University discuss findings in apoptosis.(Report)
- Newspaper article from: Biotech Week March 11, 2009 700+ words
...Zhang and colleagues, Central South University. The researchers concluded...contact Y.J. Li, Central South University, School Pharmaceutical...Therapy, Treatment, Central South University. This article was prepared...
- Research from Central South University provide new insights into stem cell...
- Newspaper article from: Angiogenesis Weekly April 24, 2009 700+ words
...Wu and colleagues, Central South University. The researchers concluded...contact G.X. Lu, Central South University, National Center Human...Tumor Vascularization, Central South University. This article was prepared...
- Scientists at Central South University describe research in hepatocellular...
- Newspaper article from: Angiogenesis Weekly March 20, 2009 700+ words
...Huang and colleagues, Central South University (see also Hepatocellular...contact G.W. Huang, Central South University, Xiangya Hospital, Dept...Endothelial Growth Factor, Central South University. This article was prepared...
- Studies from Central South University in the area of chromatography published.
- Newspaper article from: Science Letter August 5, 2008 700+ words
...Xu and colleagues, Central South University (see also Chromatography...contact B.K. Zhang, Central South University, Dept. of Clinic Pharmacy...Liquid Chromatography, Central South University. This article was prepared...
- Research from Central South University provides new data about tuberculosis.
- Newspaper article from: Obesity, Fitness & Wellness Week February 7, 2009 700+ words
...Bai and colleagues, Central South University. The researchers concluded...contact S.Y. Xiao, Central South University, School Public Health...Mycobacterium Tuberculosis, Central South University. This article was prepared...
- Reports from Central South University advance knowledge in angiogenesis.
- Newspaper article from: Angiogenesis Weekly January 2, 2009 700+ words
...Wang and colleagues, Central South University. The researchers concluded...contact L.Y. Yang, Central South University, Liver Cancer Laboratory...Endothelial Growth Factor, Central South University. This article was prepared...
- Studies from Central South University in the area of vascular disease published.
- Newspaper article from: Blood Weekly January 1, 2009 700+ words
...Tang and colleagues, Central South University (see also Vascular Disease...contact F.Y. Tang, Central South University, Xiangya Hospital 2...Treatment, Vascular Disease, Central South University. This article was prepared...
Source: HighBeam Research, Research from Central South University has provided new data on bone...