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Researchers from Safdarjung Hospital publish new studies and findings in the area of chlamydia immunology.
New investigation results, 'Serovar-specific immune responses to peptides of variable regions of Chlamydia trachomatis major outer membrane protein in serovar D-infected women,' are detailed in a study published in Clinical and Experimental Medicine. According to a study from New Delhi, India, "The role of major outer membrane protein (MOMP) variable regions in the interaction of chlamydiae and host cells has been evaluated and their role in neutralization of antibodies has been clearly demonstrated. There are also studies that delineate the contribution of these regions to the cell-mediated immune response of the host and suggest that serovar E elicits serovar-specific immune responses in infected humans."
"However, further studies with other serovars are required to confirm these findings and to elucidate the role and importance of serovar-specific responses of variable regions of MOMP in other serovars. We, therefore, performed a detailed analysis of the humoral and cellular immune responses against the serovar D-specific variable segments (VS) of MOMP in women infected with Chlamydia trachomatis. We found that VS4 elicits significantly higher responses (both humoral and cellular) than other VS peptides (VS1, VS2 and VS3)," wrote P. Srivastava and colleagues, Safdarjung Hospital (see also Chlamydia Immunology).
The researchers concluded: "VS4 elicited significantly higher (p
Srivastava and ...
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Source: HighBeam Research, Researchers from Safdarjung Hospital publish new studies and findings...