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Improving Survival When Cardiogenic Shock Complicates Acute MI.(Report)
Improving Survival When Cardiogenic Shock Complicates Acute MI
Abstract & Commentary
By David J. Pierson, MD Dr. Pierson is Director of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, Seattle Dr. Pierson reports no financial relationships with companies having ties to this field of study.
Source: Babaev A, et al. Trends in management and outcomes of patients with acute myocardial infarction complicated by cardiogenic shock. JAMA 2005;294:448-454.
Based upon the results of studies showing that early mechanical revascularization substantially reduces mortality among patients with acute myocardial infarction (AMI) complicated by cardiogenic shock, the American College of Cardiology and American Heart Association classified this intervention as a class I recommendation in their 1999 guidelines..sup.1 In this study, Babaev and colleagues used the prospectively acquired database of the National Registry of Myocardial Infarction to determine trends in the early use of early mechanical revascularization--percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) surgery--in the participating hospitals from 1995 through 2004. Of 293,633 patients treated in the participating hospitals for ST-elevation AMI during the study period, 25,311 (8.6%) had cardiogenic shock. Babaev et al examined the use of PCI and CABG in relation to outcomes in the 7356 (29%) in the latter group who had cardiogenic shock on initial presentation.
During the 10-year observation period, the rate of cardiac catheterization in this patient population increased from 51.5% to 74.4%. There were concomitant increases in the rate of primary PCI from 27.4% to 54.4%, and of total PCI from 34.3% to 64.1%, during this time. Overall CABG surgery rates decreased from 11.5% to 8.8%; the change in the rate of immediate CABG surgery from 2.1% to 3.2% was not significant. Overall in-hospital mortality fell from 60.3% in 1995 to 47.9% in 2004 (P
Commentary
- Cardiogenic Shock.
- Clinical Reference Systems Warkentin, Donald L. January 1, 2001 700+ words
...properly is called cardiogenic shock. A person who is in...chances of surviving cardiogenic shock are very small. How...The major cause of cardiogenic shock is a heart attack (myocardial infarction). A heart attack...
- Cardiogenic Shock.(Cardiology Advisor 2004.1)
- Clinical Reference Systems Warkentin, Donald L. January 1, 2004 700+ words
...properly is called cardiogenic shock. A person who is in...chances of surviving cardiogenic shock are very small. How...The major cause of cardiogenic shock is a heart attack (myocardial infarction). A heart attack...
- Cardiogenic Shock.(Cardiology Advisor 2002.1)
- Clinical Reference Systems Warkentin, Donald L. January 1, 2002 700+ words
...properly is called cardiogenic shock. A person who is in...chances of surviving cardiogenic shock are very small. How...The major cause of cardiogenic shock is a heart attack (myocardial infarction). A heart attack...
- Arginox Receives European and US Orphan Drug Designation for Cardiogenic Shock...
- Press release article from: PR Newswire Europe October 13, 2005 700+ words
...Approximately 9% of myocardial infarction patients experience...current treatments for cardiogenic shock complicating acute myocardial infarction, Dr. Frans Van de...the management of cardiogenic shock patients who have...
- Arginox Pharmaceuticals Reaches 50 Percent Enrollment Target in Its Pivotal...
- Press release article from: PR Newswire Europe May 17, 2006 700+ words
...injection in patients experiencing cardiogenic shock following reperfusion for acute myocardial infarction. Cardiogenic shock is the most common cause of...are hospitalized with an acute myocardial infarction. The TRIUMPH trial is evaluating...
- Levosimendan outshines enoximone for cardiogenic shock
- Magazine article from: Inpharma Weekly Anonymous September 6, 2008 700+ words
...survival following severe and refractory cardiogenic shock complicating acute myocardial infarction, according to researchers from Germany...evaluated for 32 patients with refractory cardiogenic shock for at least 2 hours, requiring additional...
- Research on cardiogenic shock published by R.V. Jeger et al.
- Newspaper article from: Heart Disease Weekly December 28, 2008 700+ words
...see also Cardiogenic Shock). "Analysis...AMIS (Acute Myocardial Infarction in Switzerland...Registry. Cardiogenic shock incidence...Syndrome, Cardiogenic Shock, Cardiology...Medicine, Myocardial Infarction, Therapy...
- Studies from Washington Hospital Center, Division of Cardiology have provided...
- Newspaper article from: Heart Disease Weekly August 31, 2008 700+ words
...see also Cardiogenic Shock Therapy...for acute myocardial infarction complicated...Washington, Cardiogenic Shock Therapy...Bivalirudin, Cardiogenic Shock, Cardiology...Heparin, Myocardial Infarction, Pharmaceuticals...