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Central Venous Lines Pose High Risk for Infection
Abstract & Commentary
By Jacob Ufberg, MD Dr. Ufberg is Assistant Professor of Emergency Medicine, Residency Program Director, Department of Emergency Medicine, Temple University School of Medicine, Philadelphia Dr. Ufberg reports that he is a researcher for Pfizer Pharmaceuticals.
Source: Centers for Disease Control and Prevention. Reduction in central line-associated bloodstream infections among patients in intensive care units- Pennsylvania, April 2001-March 2005. MMWR 2005;54;1013-1016.
Central line-associated bloodstream infection (BSI) is the third most common nosocomial infection reported from the medical/surgical intensive care unit (ICU) setting (after ventilator-associated pneumonia and catheter-associated urinary tract infection). Approximately 250,000 central line-associated BSIs occur annually in the United States. These lead to an estimated mortality of 12-25% and a marginal cost of $25,000 to the health care system for each infection. In 2001, the Pittsburgh Regional Healthcare Initiative (PRHI) invited the Centers for Disease Control and Prevention (CDC) to assist in a hospital-based program to prevent central line-associated BSIs among ICU patients in the region.
In 2000, PRHI formed a committee of infection-control experts to develop an infection-control intervention, targeting the elimination of central line-associated BSIs in ICUs in the region. The intervention consisted of five components: 1) promotion of evidence-based catheter insertion practices (such as the use of maximum sterile barrier precautions during insertion, use of chlorhexidine for skin preparation, avoidance of femoral catheters, use of recommended dressing practices, and removal of catheters when no longer needed); 2) development of an educational program; 3) development of standardized tools for documenting catheter insertion practices; 4) promotion of a standardized list of contents for insertion kits that included all supplies necessary to follow recommended insertion practices; and 5) measurement of central line-associated BSIs and confidential quarterly reporting of data.
To assess the effect of the intervention on the rate of BSIs, hospitals collected data on central line-associated BSIs using standardized definitions and methods during a four-year period. Thirty-two ...