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Study findings from Johns Hopkins University, Medical Department broaden understanding of hyperparathyroidism.(Report)
"Similar to other disease states, we postulated that African American patients present with more severe signs of Primary hyperparathyroidism than non-African Americans. To test this hypothesis, we compared relevant preoperative laboratory values, sestamibi scan results, and intraoperative findings between African American and non-African American patients with primary hyperparathyroidism who underwent parathyroidectomy between January 2002 and May 2007," scientists writing in the journal Surgery report (see also Hyperparathyroidism).
"In all, 588 patients were included and 113 (19%) were African American. A linear model was used to examine the effect of race with respect to mean differences in serum calcium, 25-hydroxyvitamin D (25(OH)D), intact parathyroid hormone (iPTH), alkaline phosphatase (ALKP) levels, gland weight, presence of double adenomas and, sestamibi scan sensitivity. Adjusted for age and gender, African Americans exhibited significantly higher median calcium (11.36 [SD = 0.91] vs 11.06 [SD = 0.72] mg/dL, P
The researchers concluded: "These highly significant findings, however, warrant additional investigation. (Surgery 2008,144:.1023-7.)'."
Kandil and colleagues published their study in Surgery (African Americans present with more severe primary hyperparathyroidism than non-African Americans. Surgery, 2008;144(6):1023-1026).
Additional information can be obtained by contacting M.A. Zeiger, Johns Hopkins University, School Medical, Dept. of Surgery, 600 N Wolfe St., Carnegie 681, Baltimore, MD 21287, USA.
The publisher of the journal Surgery can be ...
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