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Reports on bone research findings from Royal Perth Hospital, Medical Department provide new insights.(Clinical report)

Women's Health Weekly

| February 05, 2009 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

According to recent research from Perth, Australia, "Measurement of BMD is a key factor in calculating the risk of osteoporotic fractures. In this Practice Point commentary, I discuss the clinical implications of a Swedish population-based longitudinal observation study that examined the association between BMD and levels of bone turnover markers (BTMs) measured at inclusion and at 1, 3 and 5 year follow-up in 573 women aged 75 years."

"Baseline BTM levels showed weak correlations with total body bone loss and femoral neck bone loss over 5 years. The correlations were strengthened when the mean of the four serial BTM measurements were used. Of the seven BTMs examined, serum C-terminal cross-linked telopeptide of type I collagen was the best predictor of bone loss," wrote S.D. Vasikaran and colleagues, Royal Perth Hospital, Medical Department (see also Bone Research).

The researchers concluded: "In addition to BMD and clinical risk factors, BTM measurement with standardized sample collection may be useful for management decisions, especially in patients with borderline ...

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