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Findings in hormones reported from M. Bahceci and co-researchers.(Report)
" This study evaluated the impact of route of progesterone administration as luteal phase support on the outcome of assisted conception cycles. Intramuscular progesterone in oil (IMP) at 100 mg daily was administered to 903 women following oocyte retrieval whereas vaginal progesterone gel (VMP) at 90 mg was administered twice daily to 1,110 women," scientists in Istanbul, Turkey report (see also Hormones).
"Retrospective analysis was performed according to the type of GnRH analogue used. Implantation (IR), clinical pregnancy (CPR) and biochemical pregnancy rates (BPR) were main outcomes. In GnRH agonist cycles, neither IR, CPR or BPR differed according to the route of progesterone. However, in GnRH antagonist cycles, IR and CPR were significantly lower in VMP group compared to IMP group. BPR also was significantly higher in VMP group compared to IMP group," wrote M. Bahceci and colleagues.
The researchers concluded: " Our results suggest that route of progesterone administration for luteal phase support can be an important prognostic factor according to the type of GnRH analogue used for controlled ovarian hyperstimulation."
Bahceci and colleagues ...
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Source: HighBeam Research, Findings in hormones reported from M. Bahceci and...