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Studies from F. Sacher and colleagues yield new information about Brugada syndrome.
According to recent research published in the Journal of Cardiovascular Electrophysiology, "Women with Brugada Syndrome. Spontaneous type-1 ECG has been recognized as a risk factor for sudden cardiac death (SCD) in Brugada syndrome (BrS), but studied populations predominantly consisted of men."
"We sought to investigate whether a spontaneous type-1 ECG pattern was also associated in women with severely symptomatic BrS. Other known risk factors were also examined for gender specificity. Patients with severely symptomatic BrS, defined as resuscitated SCD and/or appropriate implantable cardioverter-defibrillator (ICD) shock, were included from 11 European centers. Clinical data, investigation of family history, 12-lead ECG, and results of electrophysiological study (EPS) were collected. The average follow-up was 4 +/- 3 years. Fifty-eight patients fulfilled the inclusion criteria (mean age 47 +/- 11 years, 8 women). Thirty-six men (72%) but only two women (25%) had a spontaneous type-1 ECG at baseline (P = 0.02). Maximal ST elevation before or after drug challenge was 3.7 +/- 1.3 mm in men versus 2.4 +/- 0.7 mm in women (P = 0.007). The proportion of patients with a family history of SCD or an SCN5A mutation was not significantly different between both groups. Of those patients with high-risk BrS who underwent EPS, 76%(12/25) of men and 50%(2/4) of women had a positive study. In ...
- Brugada Syndrome in Children.
- Magazine article from: Clinical Cardiology Alert June 1, 2007 700+ words
Brugada Syndrome in Children Abstract & Commentary...Synposis: In children affected by Brugada syndrome there is no male predominance...children in whom a diagnosis of the Brugada syndrome was made before age 16. The patients...
- Unmasking of Brugada Syndrome By Lithium.
- Magazine article from: Clinical Cardiology Alert November 1, 2005 700+ words
Unmasking of Brugada Syndrome By Lithium Abstract & Commentary...Synopsis: Lithium can unmask latent Brugada syndrome by blockade of susceptible cardiac...Darbar D, et al. Unmasking of Brugada Syndrome By Lithium. Circulation. 2005...
- Brugada syndrome in a young patient with palpitations.(Case Report/Observations...
- Magazine article from: Canadian Journal of Emergency Medicine Watrich, Deanne G. Woods, Robert A. Steiner, Ivan P. September 1, 2005 700+ words
ABSTRACT Brugada syndrome is a potentially lethal and eminently...the case of a young patient with Brugada syndrome and reviews key features in the...of this condition. Key words: Brugada syndrome; emergency medicine; ventricular...
- Case of the month: diagnostic challenges from your case files.(Brugada syndrome)
- Magazine article from: JAAPA-Journal of the American Academy of Physicians Assistants Shalshin, Alex Lo, Ronald March 1, 2006 700+ words
...Arrhythmogenic right ventricular dysplasia * Brugada syndrome * Angina pectoris DISCUSSION This patient has Brugada syndrome, an autosomal-dominant genetic...patient's ECG. The incidence of Brugada syndrome is estimated at 0.05% to 0...
- Researchers from National Taiwan University, Institute of Pharmacology discuss...
- Newspaper article from: Blood Weekly April 16, 2009 700+ words
...functional defect of three novel Brugada syndrome related cardiac sodium channel...is now available. "The Brugada syndrome is characterized by ST segment...cellular mechanisms that lead to Brugada syndrome are not yet completely understood...
- The Brugada syndrome. (Special Feature).
- Newspaper article from: Emergency Medicine Alert Brady, William J. Mattu, Amal June 1, 2003 700+ words
Introduction The Brugada syndrome is a recently described cardiac...entirely on young Asian males, the Brugada syndrome is encountered in patients of...Clinical Spectrum Patients with the Brugada syndrome experience symptomatic ventricular...
- New Brugada syndrome therapy study findings recently were published by...
- Newspaper article from: Heart Disease Weekly September 21, 2008 700+ words
...defibrillator [corrected] in patients with Brugada syndrome: a multicenter Israeli study (ISRABRU...cardioverter defibrillators for patients with Brugada syndrome who are cardiac arrest survivors or...complications of ICD therapy in patients with Brugada syndrome," scientists in Tel ...
- Abnormal response to sodium channel blockers in patients with Brugada syndrome:...
- Magazine article from: Heart Takagi, M. Aihara, N. Kuribayashi, S. Taguchi, A. Kurita, T. Suyama, K. Kamakura, S. Takamiya, M. February 1, 2003 700+ words
...channel abnormalities in cases of the Brugada syndrome. Design: Consecutive prospective...Patients: 13 consecutive patients with Brugada syndrome and 13 age and sex matched control...sodium channel. Some patients with Brugada syndrome may have arrhythmogenic substrates...
- Variable presentation of Brugada syndrome: lessons from three generations with...
- Magazine article from: British Medical Journal Plunkett, Adrian Hulse, JA Mishra, B Gill, J May 17, 2003 700+ words
...how a recently defined arrhythmia, Brugada syndrome, caused syncope in three generations...crucial to diagnosis and management. Brugada syndrome is an inherited cardiac disease causing...structurally normal heart, a diagnosis of Brugada syndrome was made. A cardioverter ...
- Reports from Tel Aviv Sourasky Medical Center highlight recent research in...
- Newspaper article from: Heart Disease Weekly August 24, 2008 700+ words
...cardioverter defribrillator in patients with Brugada syndrome: a multicenter Israeli study (ISRABRU...cardioverter defibrillators for patients with Brugada syndrome who are cardiac arrest survivors or...complications of ICD therapy in patients with Brugada syndrome." "The ...
Source: HighBeam Research, Studies from F. Sacher and colleagues yield new information about...