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Findings from K. Nakagawa and co-researchers advance knowledge in life sciences.
" To establish an index to predict ART outcomes and to identify infertile patients who need LH supplementation during ovarian stimulation. Serum LH concentrations were measured during the mid- and late-follicular phase in 86 normogonadotropic infertile patients who underwent ART treatment using GnRH-agonist long protocol with recombinant-FSH," scientists in Okura, Japan report (see also Life Sciences).
"The relationships between serum LH concentrations at both time points and ART outcomes were retrospectively analyzed, and the relationships between the ratio of late-follicular to mid-follicular LH concentrations and ART outcomes were also evaluated. There were no significant correlations between the mid- or late-follicular LH concentrations and ART outcomes. The ratio of late-follicular to mid-follicular LH concentrations = 1.0 was considered the relatively LH increased group (RI group). The number of usable embryos in RD group was similar to that in RI group, but the pregnancy and implantation rates in the RD group (9.7% and 5.8%) were significantly lower than those in the RI group (31.1% and 17.2%; p
The researchers concluded: "Therefore, the ratio of mid- to late-follicular phase LH concentrations is suggested to be an efficient index to identify patients who might ...
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Source: HighBeam Research, Findings from K. Nakagawa and co-researchers advance knowledge in...