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KUALA LUMPUR: Siew Ching Wen was given a choice - go for knee replacement surgery or lose her right leg. The 21-year-old general clerk and quality control officer was diagnosed with pigmented villonodular synovitis (PVNS) seven years ago. It is a rare disease of uncertain cause in which benign tumours grow in certain joints. Siew has so far gone through four operations to remove the growths. She has been told she needs a prosthetic knee to …