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New findings in embryo transfer described from Yamaguchi University, Medical Department.

Women's Health Weekly

| November 06, 2008 | COPYRIGHT 2008 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

In this recently published article, scientists in Ube, Japan conducted a study "To investigate the relationship between growth hormone (GH) and luteal function. In vivo comparative and in vitro culture studies. University hospital."

"Eighteen women who were interested in becoming pregnant and visited our clinic voluntarily participated in the study for urinary GH measurement. Ten women undergoing in vitro fertilization and embryo transfer (IVF-ET) were enrolled in in vitro culture studies. Ten women received IVF-ET. The GH concentrations in the urine collected for 24 hours, and serum progesterone and estradiol concentrations were measured during the midluteal phase. Effects of GH and insulin-like growth factor 1 (IGF-1) on progesterone and estradiol production were examined in the presence or absence of human chorionic gonadotropin (hCG) in human luteinized granulosa cells. Urinary GH concentrations were statistically significantly correlated with serum progesterone and estradiol concentrations. Progesterone production by luteinized granulosa cells was increased by IGF-1 (1, 10, 100 ng/mL) but not by GH (100 ng/mL) in a dose-dependent manner. Progesterone production stimulated by IGF-1 (100 ng/mL) was further increased ...

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