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Findings from J.W. Vandersteeg and co-authors broaden understanding of clinical trial research.(Clinical report)
In this recently published study, investigators in Netherlands conducted a study "To assess whether pregnancy history can predict the occurrence of a spontaneous ongoing pregnancy in subfertile couples. Prospective cohort study."
"Thirty fertility centers in the Netherlands. Subfertile, ovulatory women with at least one patent tube and male partners without severely impaired semen quality. Fertility work-up, including a detailed pregnancy history. Spontaneous ongoing pregnancy. We included 4445 couples, of whom 793 (18%) had a spontaneous ongoing pregnancy within 1 year of follow-up. Previous live birth and miscarriage in current partnership were both associated with higher fecundity as compared with primary infertility (hazard rate ratios for spontaneous pregnancy [HR] 1.4; 95% CI, 1.2-1.7 and 1.3; 95% CI, 1.0-1.5, respectively). Pregnancies in a woman's previous partnerships did not affect the fecundity of the couple. A pregnancy in a previous partnership of the male partner was associated with lower fecundity (HR 0.76; 95% CI, 0.58-0.99). A previous pregnancy after fertility treatment also was associated with lower fecundity (HR ...
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Source: HighBeam Research, Findings from J.W. Vandersteeg and co-authors broaden understanding...